Karakterisasi Simplisia dan Standarisasi Ekstrak Air Daun Ndusuk (Melastoma malabathricum L.)

Alya Khairunnisa; Muhajirin Dena; Alya Khairunnisa; Muhajirin Dena

doi:10.32665/faskes.v4i1.7157

Authors

Alya Khairunnisa Universitas Nusa Cendana
Muhajirin Dena Nusa Cendana University

DOI:

https://doi.org/10.32665/faskes.v4i1.7157

Keywords:

Melastoma malabathricum L., Ndusuk, quercetin

Abstract

Latar Belakang: Daun Ndusuk (Melastoma malabathricum L.) berpotensi sebagai bahan baku obat tradisional, namun pengembangannya memerlukan data karakterisasi simplisia dan standardisasi ekstrak air untuk menjamin mutu. Tujuan: Mengarakterisasi simplisia dan menstandardisasi ekstrak air daun Ndusuk dengan karakterisasi dilakukan secara makroskopis-mikroskopis serta standarisasi meliputi parameter spesifik maupun nonspesifik. Metode: Ekstrak diperoleh melalui metode infusa menggunakan air pada suhu 90°C selama 15 menit dengan pengujian menggunakan spektrofotometri UV-Vis. Hasil: Simplisia memiliki fragmen pengenal berupa trikomata, stomata, berkas pengangkut berkristal kalsium oksalat roset, dan sklerenkim. Rendemen ekstrak sebesar 13,49%, berwarna cokelat kehitaman, bau aromatik, dan rasa pahit. Kadar sari larut air 67,26±1,07%, kadar sari larut etanol 14,06±1,29%, dan kadar kuersetin 9,61 mg/g. Susut pengeringan 4,44±0,26%, kadar air 6,72±0,27%, kadar abu total 9,11±0,07%, kadar abu tidak larut asam 0,06±0,09%, bobot jenis 0,975±0,01, cemaran mikroba ALT 4,75×10⁴ CFU/mL, kadmium 0,06 mg/kg, dan timbal 0,51 mg/kg. Kesimpulan: Seluruh parameter memenuhi persyaratan mutu. Saran: Mengkaji aktivitas biologis ekstrak air daun Ndusuk untuk melengkapi data karakterisasi dan standarisasi yang telah diperoleh.

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